COVID 19

Current stage: Phase 1
Platform	Type of candidate vaccine	Developer
Non- Replicating Viral Vector	Adenovirus Type 5 Vector	CanSino Biological Inc. and Beijing Institute of Biotechnology
RNA	LNP- encapsulated mRNA	Moderna/NIAID
Current stage: Pre-clinical
Platform	Type of candidate vaccine	Developer
DNA	DNA plasmid vaccine Electroporation device	Inovio Pharmaceuticals
DNA	DNA	Takis/Applied DNA Sciences/Evvivax
DNA	DNA plasmid vaccine	Zydus Cadila
Inactivated	Formaldehyde- inactivated + alum	Sinovac
Live Attenuated Virus	Deoptimized live attanuated vaccines	Codagenix/Serum Institute of India
Non- Replicating Viral Vector	MVA encoded VLP	GeoVax/BravoVax
Non- Replicating Viral Vector	Ad26 (alone or with MVA boost)	Janssen Pharmaceutical Companies
Non- Replicating Viral Vector	ChAdOx1	University of Oxford
Non- Replicating Viral Vector	adenovirus- based NasoVAX expressing SARS2-CoV spike protein	Altimmune
Non- Replicating Viral Vector	Ad5 S (GREVAX™ platform)	Greffex
Non- Replicating Viral Vector	Oral Vaccine platform	Vaxart
Protein Subunit	Drosophila S2 insect cell expression system VLPs	ExpreS2ion
Protein Subunit	S protein	WRAIR/USAMRIID
Protein Subunit	S-Trimer	Clover Biopharmaceuticals Inc./GSK
Protein Subunit	Peptide	Vaxil Bio
Protein Subunit	S protein	AJ Vaccines
Protein Subunit	Ii-Key peptide	Generex/EpiVax
Protein Subunit	S protein	EpiVax/Univ. of Georgia
Protein Subunit	S protein (baculovirus production)	Sanofi Pasteur
Protein Subunit	Full length S trimers/ nanoparticle + Matrix M	Novavax
Protein Subunit	gp-96 backbone	Heat Biologics/Univ. Of Miami
Protein Subunit	Molecular clamp stabilized Spike protein	University of Queensland/GSK
Protein Subunit	S1 or RBD protein	Baylor College of Medicine
Protein Subunit	Subunit protein, plant produced	iBio/CC-Pharming
Protein Subunit	Subunit	VIDO-InterVac, University of Saskatchewan
Protein Subunit	Adjuvanted microsphere peptide	University of Saskatchewan
Replicating Viral Vector	Measles Vector	Zydus Cadila
Replicating Viral Vector	Measles Vector	Institute Pasteur/Themis/Univ. of Pittsburg Center for Vaccine Research
Replicating Viral Vector	Horsepox vector expressing S protein	Tonix Pharma/Southern Research
RNA	LNP- encapsulated mRNA cocktail encoding VLP	Fudan University/ Shanghai JiaoTong University/RNACure Biopharma
RNA	LNP- encapsulated mRNA encoding RBD	Fudan University/ Shanghai JiaoTong University/RNACure Biopharma
RNA	mRNA	China CDC/Tongji University/Stermina
RNA	mRNA	Arcturus/Duke-NUS
RNA	mRNA	BioNTech/Fosun Pharma/Pfizer
RNA	saRNA	Imperial College London
RNA	mRNA	Curevac
VLP	Plant-derived VLP	Medicago Inc.
Unknown	Unknown	University of Hong Kong
Unknown	Unknown	ImmunoPrecise
Unknown	Unknown	MIGAL Galilee Research Institute
Unknown	Unknown	Doherty Institute
Unknown	Unknown	Tulane University

All vaccines are targetted at COVID-19

Table of contents Ministry of Health &
Family Welfare Kerala Data : By C-DIT Situation Report : WHO Corona About outbreak Virus Morphology Transmission Pathophysiology Clinical Features Red flag signs Treatment Vaccines Definition of case Classification of contacts Classification of risk Clinical Categorization Treatment Guidelines UIP Guidelines Advisory for Pregnancy Quarantine & Testing IEC materials Drug prophylaxis FAQs Government Orders

Use of masks in the community

PPE Guidelines

Donning of PPE

Ref: https://www.who.int/blueprint/priority-diseases/key-action/novel-coronavirus-landscape-ncov.pdf?ua=1

Coronavirus Disease 2019 - COVID 19

Candidate Vaccines